E-ISSN 2218-6050 | ISSN 2226-4485
 

Original Research


Studies on the antidiarrhoeal, antimicrobial and cytotoxic activities of ethanol-extracted leaves of yellow oleander (Thevetia peruviana)

M.m. Hassan1, *, A.k. Saha1, S.a. Khan1, A. Islam1, M. Mahabub-uz-zaman2 And S.s.u. Ahmed3.


Cited By:44

Abstract
This study screened the antidiarrhoeal, antimicrobial and cytotoxic effects of ethanol-extracted leaves of yellow oleander (Thevetia peruviana). The extract was tested against castor oil-induced diarrhoea in a model of albino rats and showed significant antidiarrhoeal activity (P<0.01). Disc diffusion technique was used to test the in vitro antibacterial activities of the extract and exhibited poor antibacterial activities against both Gram positive and Gram negative bacteria (mainly Bacillus sp). Ethanol-extracted leaves of yellow oleander showed narrow zone of inhibition in the bacterial lawns of Shigella flexineri, Salmonella typhi, Klebsiella sp, Staphylococcus aureus and Shigella sonnei. Cytotoxicty was determined against brine shrimp nauplii and LC50 of the plant extract was determined as 627.21�g/ml. The wide range of LC50 value denotes the safety effect of the extract.

Key words: Antidiarrhoeal, Antimicrobial, Cytotoxicity, Albino rats, Brine shrimp, Yellow oleander, LC50


 
ARTICLE TOOLS
Abstract
PDF Fulltext
How to cite this articleHow to cite this article
Citation Tools
Related Records
 Articles by M.M. Hassan1
Articles by *
Articles by A.K. Saha1
Articles by S.A. Khan1
Articles by A. Islam1
Articles by M. Mahabub-Uz-Zaman2 and S.S.U. Ahmed3
on Google
on Google Scholar


How to Cite this Article
Pubmed Style

Hassan M, , Saha A, Khan S, Islam A, Ahmed MMAS. Studies on the antidiarrhoeal, antimicrobial and cytotoxic activities of ethanol-extracted leaves of yellow oleander (Thevetia peruviana). Open Vet J. 2011; 1(0): 28-31. doi:10.5455/OVJ.2011.v1.i0.p28


Web Style

Hassan M, , Saha A, Khan S, Islam A, Ahmed MMAS. Studies on the antidiarrhoeal, antimicrobial and cytotoxic activities of ethanol-extracted leaves of yellow oleander (Thevetia peruviana). https://www.openveterinaryjournal.com/?mno=302656804 [Access: May 09, 2025]. doi:10.5455/OVJ.2011.v1.i0.p28


AMA (American Medical Association) Style

Hassan M, , Saha A, Khan S, Islam A, Ahmed MMAS. Studies on the antidiarrhoeal, antimicrobial and cytotoxic activities of ethanol-extracted leaves of yellow oleander (Thevetia peruviana). Open Vet J. 2011; 1(0): 28-31. doi:10.5455/OVJ.2011.v1.i0.p28



Vancouver/ICMJE Style

Hassan M, , Saha A, Khan S, Islam A, Ahmed MMAS. Studies on the antidiarrhoeal, antimicrobial and cytotoxic activities of ethanol-extracted leaves of yellow oleander (Thevetia peruviana). Open Vet J. (2011), [cited May 09, 2025]; 1(0): 28-31. doi:10.5455/OVJ.2011.v1.i0.p28



Harvard Style

Hassan, M., , ., Saha, . A., Khan, . S., Islam, . A. & Ahmed, . M. M. A. S. (2011) Studies on the antidiarrhoeal, antimicrobial and cytotoxic activities of ethanol-extracted leaves of yellow oleander (Thevetia peruviana). Open Vet J, 1 (0), 28-31. doi:10.5455/OVJ.2011.v1.i0.p28



Turabian Style

Hassan, M.m., , A.k. Saha, S.a. Khan, A. Islam, and M. Mahabub-uz-zaman And S.s.u. Ahmed. 2011. Studies on the antidiarrhoeal, antimicrobial and cytotoxic activities of ethanol-extracted leaves of yellow oleander (Thevetia peruviana). Open Veterinary Journal, 1 (0), 28-31. doi:10.5455/OVJ.2011.v1.i0.p28



Chicago Style

Hassan, M.m., , A.k. Saha, S.a. Khan, A. Islam, and M. Mahabub-uz-zaman And S.s.u. Ahmed. "Studies on the antidiarrhoeal, antimicrobial and cytotoxic activities of ethanol-extracted leaves of yellow oleander (Thevetia peruviana)." Open Veterinary Journal 1 (2011), 28-31. doi:10.5455/OVJ.2011.v1.i0.p28



MLA (The Modern Language Association) Style

Hassan, M.m., , A.k. Saha, S.a. Khan, A. Islam, and M. Mahabub-uz-zaman And S.s.u. Ahmed. "Studies on the antidiarrhoeal, antimicrobial and cytotoxic activities of ethanol-extracted leaves of yellow oleander (Thevetia peruviana)." Open Veterinary Journal 1.0 (2011), 28-31. Print. doi:10.5455/OVJ.2011.v1.i0.p28



APA (American Psychological Association) Style

Hassan, M., , ., Saha, . A., Khan, . S., Islam, . A. & Ahmed, . M. M. A. S. (2011) Studies on the antidiarrhoeal, antimicrobial and cytotoxic activities of ethanol-extracted leaves of yellow oleander (Thevetia peruviana). Open Veterinary Journal, 1 (0), 28-31. doi:10.5455/OVJ.2011.v1.i0.p28