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Chlorpyrifos chronic toxicity in broilers and effect of vitamin C

A.M. Kammon1,*, R.S. Brar2, S. Sodhi2, H.S. Banga2, J. Singh3 and N.S. Nagra4.


Abstract
An experiment was conducted to study chlorpyrifos chronic toxicity in broilers and the protective effect of vitamin C. Oral administration of 0.8 mg/kg body weight (bw) (1/50 LD50) chlorpyrifos (Radar�), produced mild diarrhea and gross lesions comprised of paleness, flaccid consistency and slightly enlargement of liver. Histopathologically, chlorpyrifos produced degenerative changes in various organs. Oral administration of 100 mg/kg bw vitamin C partially ameliorated the degenerative changes in kidney and heart. There was insignificant alteration in biochemical and haematological profiles. It is concluded that supplementation of vitamin C reduced the severity of lesions induced by chronic chlorpyrifos toxicity in broilers.

Key words: chlorpyrifos, chronic toxicity, clinicopathology, vitamin C, broilers.


 
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How to Cite this Article
Pubmed Style

A.M. Kammon,, R.S. Brar, S. Sodhi, H.S. Banga, J. Singh and N.S. Nagra. Chlorpyrifos chronic toxicity in broilers and effect of vitamin C. Open Vet J. 2011; 1(0): 21-27. doi:10.5455/OVJ.2011.v1.i0.p21

Web Style

A.M. Kammon,, R.S. Brar, S. Sodhi, H.S. Banga, J. Singh and N.S. Nagra. Chlorpyrifos chronic toxicity in broilers and effect of vitamin C. https://www.openveterinaryjournal.com/?mno=302656803 [Access: April 09, 2024]. doi:10.5455/OVJ.2011.v1.i0.p21

AMA (American Medical Association) Style

A.M. Kammon,, R.S. Brar, S. Sodhi, H.S. Banga, J. Singh and N.S. Nagra. Chlorpyrifos chronic toxicity in broilers and effect of vitamin C. Open Vet J. 2011; 1(0): 21-27. doi:10.5455/OVJ.2011.v1.i0.p21


Vancouver/ICMJE Style

A.M. Kammon,, R.S. Brar, S. Sodhi, H.S. Banga, J. Singh and N.S. Nagra. Chlorpyrifos chronic toxicity in broilers and effect of vitamin C. Open Vet J. (2011), [cited April 09, 2024]; 1(0): 21-27. doi:10.5455/OVJ.2011.v1.i0.p21


Harvard Style

A.M. Kammon,, R.S. Brar, S. Sodhi, H.S. Banga, J. Singh and N.S. Nagra (2011) Chlorpyrifos chronic toxicity in broilers and effect of vitamin C. Open Vet J, 1 (0), 21-27. doi:10.5455/OVJ.2011.v1.i0.p21


Turabian Style

A.M. Kammon,, R.S. Brar, S. Sodhi, H.S. Banga, J. Singh and N.S. Nagra. 2011. Chlorpyrifos chronic toxicity in broilers and effect of vitamin C. Open Veterinary Journal, 1 (0), 21-27. doi:10.5455/OVJ.2011.v1.i0.p21


Chicago Style

A.M. Kammon,, R.S. Brar, S. Sodhi, H.S. Banga, J. Singh and N.S. Nagra. "Chlorpyrifos chronic toxicity in broilers and effect of vitamin C." Open Veterinary Journal 1 (2011), 21-27. doi:10.5455/OVJ.2011.v1.i0.p21


MLA (The Modern Language Association) Style

A.M. Kammon,, R.S. Brar, S. Sodhi, H.S. Banga, J. Singh and N.S. Nagra. "Chlorpyrifos chronic toxicity in broilers and effect of vitamin C." Open Veterinary Journal 1.0 (2011), 21-27. Print. doi:10.5455/OVJ.2011.v1.i0.p21


APA (American Psychological Association) Style

A.M. Kammon,, R.S. Brar, S. Sodhi, H.S. Banga, J. Singh and N.S. Nagra (2011) Chlorpyrifos chronic toxicity in broilers and effect of vitamin C. Open Veterinary Journal, 1 (0), 21-27. doi:10.5455/OVJ.2011.v1.i0.p21


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