E-ISSN 2218-6050 | ISSN 2226-4485
 

Research Article


Antimicrobial resistance from one health perspective in the Middle East: A systematic review

Khalid A. Alkheraije.


Abstract
Background:
Antimicrobial resistance (AMR) is recognized globally as a significant health challenge, but its extent remains unclear in many regions. It is crucial to prioritize a foundational evaluation of AMR prevalence to facilitate the implementation of laboratory-based surveillance. Adopting a One Health perspective, this study outlines the present AMR status in the Middle East.
Aim:
To synthesize the current state of knowledge on AMR in the Middle East, delineate the contributions of different sectors (human health, animal health, and environment), and discern the effectiveness of One Health interventions in mitigating AMR.
Methods:
An exhaustive literature search was conducted via PubMed, ScienceDirect, and Google Scholar. Potential articles were screened and assessed for eligibility based on prescribed eligibility criteria. Data synthesis was done, and the results were reported and discussed thematically.
Results:
Twenty-three studies were included in the study and published between 2019 and 2023. Most studies reveal substantial challenges in treating infections, with a significant prevalence of resistance in critical care units, particularly against ESBL and carbapenem-resistant Gram-Negative Bacteria. Colistin and imipenem resistance in pediatric populations further emphasize the urgency of understanding and addressing diverse resistance mechanisms in the region. Studies on urinary pathogens, bacteremia, and biofilm formation highlight the multifaceted challenge of antimicrobial resistance. The emergence of resistance to key antibiotics emphasizes the urgency for tailored treatment strategies.
Conclusion:
Given the interconnectedness of human, animal, and environmental health, a One Health perspective is imperative. The diverse challenge demands coordinated efforts, including innovative interventions and public health policies. Bridging existing gaps through future research is crucial for evidence-based and context-specific strategies in combating antimicrobial resistance in the region.

Key words: Antimicrobial resistance, One health, Middle East


 
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Pubmed Style

Alkheraije KA, . Antimicrobial resistance from one health perspective in the Middle East: A systematic review. Open Vet J. 2024; 14((1) (Zagazig Veterinary Conference)): 577-585. doi:10.5455/OVJ.2024.v14.i1.53


Web Style

Alkheraije KA, . Antimicrobial resistance from one health perspective in the Middle East: A systematic review. https://www.openveterinaryjournal.com/?mno=188605 [Access: June 22, 2024]. doi:10.5455/OVJ.2024.v14.i1.53


AMA (American Medical Association) Style

Alkheraije KA, . Antimicrobial resistance from one health perspective in the Middle East: A systematic review. Open Vet J. 2024; 14((1) (Zagazig Veterinary Conference)): 577-585. doi:10.5455/OVJ.2024.v14.i1.53



Vancouver/ICMJE Style

Alkheraije KA, . Antimicrobial resistance from one health perspective in the Middle East: A systematic review. Open Vet J. (2024), [cited June 22, 2024]; 14((1) (Zagazig Veterinary Conference)): 577-585. doi:10.5455/OVJ.2024.v14.i1.53



Harvard Style

Alkheraije, K. A. & (2024) Antimicrobial resistance from one health perspective in the Middle East: A systematic review. Open Vet J, 14 ((1) (Zagazig Veterinary Conference)), 577-585. doi:10.5455/OVJ.2024.v14.i1.53



Turabian Style

Alkheraije, Khalid A., and . 2024. Antimicrobial resistance from one health perspective in the Middle East: A systematic review. Open Veterinary Journal, 14 ((1) (Zagazig Veterinary Conference)), 577-585. doi:10.5455/OVJ.2024.v14.i1.53



Chicago Style

Alkheraije, Khalid A., and . "Antimicrobial resistance from one health perspective in the Middle East: A systematic review." Open Veterinary Journal 14 (2024), 577-585. doi:10.5455/OVJ.2024.v14.i1.53



MLA (The Modern Language Association) Style

Alkheraije, Khalid A., and . "Antimicrobial resistance from one health perspective in the Middle East: A systematic review." Open Veterinary Journal 14.(1) (Zagazig Veterinary Conference) (2024), 577-585. Print. doi:10.5455/OVJ.2024.v14.i1.53



APA (American Psychological Association) Style

Alkheraije, K. A. & (2024) Antimicrobial resistance from one health perspective in the Middle East: A systematic review. Open Veterinary Journal, 14 ((1) (Zagazig Veterinary Conference)), 577-585. doi:10.5455/OVJ.2024.v14.i1.53