E-ISSN 2218-6050 | ISSN 2226-4485
 

Case Report


Successful treatment and long-term follow-up of a young cat with feline infectious peritonitis and renal lymphoma

Ilse Beekhuis, Goncalos Serrano, Angel Almendros, Antonio Giuliano.


Abstract
Background:
Feline lymphoma is often a fatal disease and the possibility of achieving a cure with chemotherapy is questionable. A diagnosis of FIP was historically associated with a poor prognosis and high mortality, but with the newly available treatment, remission is possible. Long-term follow-up data on treated cases remain limited.

Case description:
A 3.9-year-old neutered male cat was presented with hyporexia and lethargy lasting several days. An abdominal mass was palpated on clinical examination and confirmed to be a renal mass on a computed tomography angiography (CTA) scan. Ultrasound-guided fine needle aspirates were performed, and cytological evaluation revealed a large-cell renal lymphoma. A modified COP protocol with the addition of vinblastine (COVP protocol) was started, resulting in a complete response. Twenty weeks after starting chemotherapy, the cat developed anorexia, fever, and pleural effusion. Feline infectious peritonitis (FIP) was diagnosed based on a positive RT RNA PCR test from the pleural effusion. Subcutaneous GS441524 administration led to FIP resolution.

Conclusion:
The cat did not receive any further treatment for both FIP and lymphoma and is still alive and well, almost 5 years after the diagnosis. To the author's knowledge, this is the first case of renal lymphoma in a cat that subsequently developed FIP. Further studies on the potential correlation of lymphoma, chemotherapy and FIP are needed.

Key words: CHOP protocol; FIP; Remdesivir; Renal lymphoma.


 
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How to Cite this Article
Pubmed Style

Beekhuis I, Serrano G, Almendros A, Giuliano A. Successful treatment and long-term follow-up of a young cat with feline infectious peritonitis and renal lymphoma. Open Vet. J.. 2025; 15(10): 5383-5390. doi:10.5455/OVJ.2025.v15.i10.56


Web Style

Beekhuis I, Serrano G, Almendros A, Giuliano A. Successful treatment and long-term follow-up of a young cat with feline infectious peritonitis and renal lymphoma. https://www.openveterinaryjournal.com/?mno=239304 [Access: June 26, 2026]. doi:10.5455/OVJ.2025.v15.i10.56


AMA (American Medical Association) Style

Beekhuis I, Serrano G, Almendros A, Giuliano A. Successful treatment and long-term follow-up of a young cat with feline infectious peritonitis and renal lymphoma. Open Vet. J.. 2025; 15(10): 5383-5390. doi:10.5455/OVJ.2025.v15.i10.56



Vancouver/ICMJE Style

Beekhuis I, Serrano G, Almendros A, Giuliano A. Successful treatment and long-term follow-up of a young cat with feline infectious peritonitis and renal lymphoma. Open Vet. J.. (2025), [cited June 26, 2026]; 15(10): 5383-5390. doi:10.5455/OVJ.2025.v15.i10.56



Harvard Style

Beekhuis, I., Serrano, . G., Almendros, . A. & Giuliano, . A. (2025) Successful treatment and long-term follow-up of a young cat with feline infectious peritonitis and renal lymphoma. Open Vet. J., 15 (10), 5383-5390. doi:10.5455/OVJ.2025.v15.i10.56



Turabian Style

Beekhuis, Ilse, Goncalos Serrano, Angel Almendros, and Antonio Giuliano. 2025. Successful treatment and long-term follow-up of a young cat with feline infectious peritonitis and renal lymphoma. Open Veterinary Journal, 15 (10), 5383-5390. doi:10.5455/OVJ.2025.v15.i10.56



Chicago Style

Beekhuis, Ilse, Goncalos Serrano, Angel Almendros, and Antonio Giuliano. "Successful treatment and long-term follow-up of a young cat with feline infectious peritonitis and renal lymphoma." Open Veterinary Journal 15 (2025), 5383-5390. doi:10.5455/OVJ.2025.v15.i10.56



MLA (The Modern Language Association) Style

Beekhuis, Ilse, Goncalos Serrano, Angel Almendros, and Antonio Giuliano. "Successful treatment and long-term follow-up of a young cat with feline infectious peritonitis and renal lymphoma." Open Veterinary Journal 15.10 (2025), 5383-5390. Print. doi:10.5455/OVJ.2025.v15.i10.56



APA (American Psychological Association) Style

Beekhuis, I., Serrano, . G., Almendros, . A. & Giuliano, . A. (2025) Successful treatment and long-term follow-up of a young cat with feline infectious peritonitis and renal lymphoma. Open Veterinary Journal, 15 (10), 5383-5390. doi:10.5455/OVJ.2025.v15.i10.56