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2025, Vol: 15, Issue: 4
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Case Report


A spontaneous ovarian teratoma in an FVB/n female mouse: Case report and literature review

Paula Alexandra Martins De-oliveira, Ana I. Faustino-rocha, Rui M. Gil Da-costa, Elisabete Nascimento Gonçalves, Ana Margarida Calado, Catarina Jota Baptista, Adelina Gama, Fernanda Seixas.


Cited By:2

Abstract
Background:
Teratomas are rare types of germ cell neoplasms composed of various differentiated or undifferentiated tissues.
Case Description:
A 25-week-old female control FVB/n mouse in a 4-week toxicity study presented abdominal distension and poor body condition. It was euthanized, and the necropsy exam revealed a large mass connected to the tip of the right uterine horn, occupying the entire abdominal cavity. Microscopically, this mass showed areas of epidermal differentiation, with laminated keratin and sebaceous glands, differentiation into respiratory and digestive epithelium, cartilage, bone, and extensive areas of differentiation into the nervous tissue, being classified as an ovarian teratoma.
Conclusion:
As far as authors know, the occurrence of ovarian teratomas in FVB/n mouse strain has never been previously described.

Key words: Mouse, Ovary, Rodent, Teratoma


 
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How to Cite this Article
Pubmed Style

De-oliveira PAM, Faustino-rocha AI, Da-costa RMG, Goncalves EN, Calado AM, Baptista CJ, Gama A, Seixas F. A spontaneous ovarian teratoma in an FVB/n female mouse: Case report and literature review. Open Vet J. 2023; 13(9): 1223-1227. doi:10.5455/OVJ.2023.v13.i9.19

Web Style

De-oliveira PAM, Faustino-rocha AI, Da-costa RMG, Goncalves EN, Calado AM, Baptista CJ, Gama A, Seixas F. A spontaneous ovarian teratoma in an FVB/n female mouse: Case report and literature review. https://www.openveterinaryjournal.com/?mno=147336 [Access: May 08, 2025]. doi:10.5455/OVJ.2023.v13.i9.19

AMA (American Medical Association) Style

De-oliveira PAM, Faustino-rocha AI, Da-costa RMG, Goncalves EN, Calado AM, Baptista CJ, Gama A, Seixas F. A spontaneous ovarian teratoma in an FVB/n female mouse: Case report and literature review. Open Vet J. 2023; 13(9): 1223-1227. doi:10.5455/OVJ.2023.v13.i9.19


Vancouver/ICMJE Style

De-oliveira PAM, Faustino-rocha AI, Da-costa RMG, Goncalves EN, Calado AM, Baptista CJ, Gama A, Seixas F. A spontaneous ovarian teratoma in an FVB/n female mouse: Case report and literature review. Open Vet J. (2023), [cited May 08, 2025]; 13(9): 1223-1227. doi:10.5455/OVJ.2023.v13.i9.19


Harvard Style

De-oliveira, P. A. M., Faustino-rocha, . A. I., Da-costa, . R. M. G., Goncalves, . E. N., Calado, . A. M., Baptista, . C. J., Gama, . A. & Seixas, . F. (2023) A spontaneous ovarian teratoma in an FVB/n female mouse: Case report and literature review. Open Vet J, 13 (9), 1223-1227. doi:10.5455/OVJ.2023.v13.i9.19


Turabian Style

De-oliveira, Paula Alexandra Martins, Ana I. Faustino-rocha, Rui M. Gil Da-costa, Elisabete Nascimento Goncalves, Ana Margarida Calado, Catarina Jota Baptista, Adelina Gama, and Fernanda Seixas. 2023. A spontaneous ovarian teratoma in an FVB/n female mouse: Case report and literature review. Open Veterinary Journal, 13 (9), 1223-1227. doi:10.5455/OVJ.2023.v13.i9.19


Chicago Style

De-oliveira, Paula Alexandra Martins, Ana I. Faustino-rocha, Rui M. Gil Da-costa, Elisabete Nascimento Goncalves, Ana Margarida Calado, Catarina Jota Baptista, Adelina Gama, and Fernanda Seixas. "A spontaneous ovarian teratoma in an FVB/n female mouse: Case report and literature review." Open Veterinary Journal 13 (2023), 1223-1227. doi:10.5455/OVJ.2023.v13.i9.19


MLA (The Modern Language Association) Style

De-oliveira, Paula Alexandra Martins, Ana I. Faustino-rocha, Rui M. Gil Da-costa, Elisabete Nascimento Goncalves, Ana Margarida Calado, Catarina Jota Baptista, Adelina Gama, and Fernanda Seixas. "A spontaneous ovarian teratoma in an FVB/n female mouse: Case report and literature review." Open Veterinary Journal 13.9 (2023), 1223-1227. Print. doi:10.5455/OVJ.2023.v13.i9.19


APA (American Psychological Association) Style

De-oliveira, P. A. M., Faustino-rocha, . A. I., Da-costa, . R. M. G., Goncalves, . E. N., Calado, . A. M., Baptista, . C. J., Gama, . A. & Seixas, . F. (2023) A spontaneous ovarian teratoma in an FVB/n female mouse: Case report and literature review. Open Veterinary Journal, 13 (9), 1223-1227. doi:10.5455/OVJ.2023.v13.i9.19


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