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Research Article


Vitamin-supplemented medical-grade honey for burn wound management in cats and dogs: a retrospective case series

Alexandra Peteoacă, Stathis A. Symeonidis, Vasiliki Tachmatzidou, Noëlle A. C. J. M. Paping, Carlos C. F. Pleeging, Linsey J. F. Peters, Niels A. J. Cremers.


Abstract
Background:
Burn wounds in companion animals are uncommon but can lead to serious complications and be lifethreatening, requiring prompt and effective wound care. Conventional treatment methods often involve silver- or antibiotic-based products, which carry disadvantages such as cytotoxicity and risk of antimicrobial resistance. Medicalgrade honey (MGH), especially when supplemented with vitamins C and E, offers a potential alternative due to its antimicrobial, anti-inflammatory, and wound-healing properties.

Aim:
This study aims to evaluate the clinical outcomes of vitamin-supplemented MGH in the management of burn wounds in cats and dogs.

Methods:
A retrospective, multi-center case series was conducted across three veterinary clinics in Romania, Greece, and the Netherlands. Nine cases involving cats (n = 4) and dogs (n = 5) with thermal, chemical, or iatrogenic burn wounds were included. All wounds were treated with MGH-based products (L-Mesitran range), and wound progression was documented photographically. Descriptive statistics (mean ± SD) were calculated for key parameters, including time to visible inflammation reduction, debridement, granulation tissue formation, re-epithelialization, and complete
healing.

Results:
All patients achieved complete wound healing without complications. On average, signs of inflammation reduced within 5.2 ± 2.0 days (mean ± SD), debridement occurred in 6.7 ± 2.2 days, granulation tissue appeared after 11.7 ± 4.1 days, re-epithelialization was shown in 23.6 ± 5.9 days, and full wound closure was achieved in 64.7 ± 20.7 days. These clinical outcomes varied between individual cases, depending on wound age, size, severity, location, and patient characteristics.

Conclusion:
Vitamin-supplemented MGH showed promising outcomes in promoting wound healing in feline and canine burn patients. However, the small sample size, retrospective design, and lack of a control group limit the generalizability of these findings.

Key words: Burns; Cats; Dogs; Medical-grade honey; Wound healing.


 
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How to Cite this Article
Pubmed Style

Peteoacă A, Symeonidis SA, Tachmatzidou V, , Pleeging CCF, Peters LJF, Cremers NAJ. Vitamin-supplemented medical-grade honey for burn wound management in cats and dogs: a retrospective case series. Open Vet. J.. 2026; 16(1): 653-668. doi:10.5455/OVJ.2026.v16.i1.61

Web Style

Peteoacă A, Symeonidis SA, Tachmatzidou V, , Pleeging CCF, Peters LJF, Cremers NAJ. Vitamin-supplemented medical-grade honey for burn wound management in cats and dogs: a retrospective case series. https://www.openveterinaryjournal.com/?mno=271656 [Access: February 04, 2026]. doi:10.5455/OVJ.2026.v16.i1.61

AMA (American Medical Association) Style

Peteoacă A, Symeonidis SA, Tachmatzidou V, , Pleeging CCF, Peters LJF, Cremers NAJ. Vitamin-supplemented medical-grade honey for burn wound management in cats and dogs: a retrospective case series. Open Vet. J.. 2026; 16(1): 653-668. doi:10.5455/OVJ.2026.v16.i1.61


Vancouver/ICMJE Style

Peteoacă A, Symeonidis SA, Tachmatzidou V, , Pleeging CCF, Peters LJF, Cremers NAJ. Vitamin-supplemented medical-grade honey for burn wound management in cats and dogs: a retrospective case series. Open Vet. J.. (2026), [cited February 04, 2026]; 16(1): 653-668. doi:10.5455/OVJ.2026.v16.i1.61


Harvard Style

Peteoacă, A., Symeonidis, . S. A., Tachmatzidou, . V., , Pleeging, . C. C. F., Peters, . L. J. F. & Cremers, . N. A. J. (2026) Vitamin-supplemented medical-grade honey for burn wound management in cats and dogs: a retrospective case series. Open Vet. J., 16 (1), 653-668. doi:10.5455/OVJ.2026.v16.i1.61


Turabian Style

Peteoacă, Alexandra, Stathis A. Symeonidis, Vasiliki Tachmatzidou, Noëlle A. C. J. M. Paping, Carlos C. F. Pleeging, Linsey J. F. Peters, and Niels A. J. Cremers. 2026. Vitamin-supplemented medical-grade honey for burn wound management in cats and dogs: a retrospective case series. Open Veterinary Journal, 16 (1), 653-668. doi:10.5455/OVJ.2026.v16.i1.61


Chicago Style

Peteoacă, Alexandra, Stathis A. Symeonidis, Vasiliki Tachmatzidou, Noëlle A. C. J. M. Paping, Carlos C. F. Pleeging, Linsey J. F. Peters, and Niels A. J. Cremers. "Vitamin-supplemented medical-grade honey for burn wound management in cats and dogs: a retrospective case series." Open Veterinary Journal 16 (2026), 653-668. doi:10.5455/OVJ.2026.v16.i1.61


MLA (The Modern Language Association) Style

Peteoacă, Alexandra, Stathis A. Symeonidis, Vasiliki Tachmatzidou, Noëlle A. C. J. M. Paping, Carlos C. F. Pleeging, Linsey J. F. Peters, and Niels A. J. Cremers. "Vitamin-supplemented medical-grade honey for burn wound management in cats and dogs: a retrospective case series." Open Veterinary Journal 16.1 (2026), 653-668. Print. doi:10.5455/OVJ.2026.v16.i1.61


APA (American Psychological Association) Style

Peteoacă, A., Symeonidis, . S. A., Tachmatzidou, . V., , Pleeging, . C. C. F., Peters, . L. J. F. & Cremers, . N. A. J. (2026) Vitamin-supplemented medical-grade honey for burn wound management in cats and dogs: a retrospective case series. Open Veterinary Journal, 16 (1), 653-668. doi:10.5455/OVJ.2026.v16.i1.61


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