E-ISSN 2218-6050 | ISSN 2226-4485
 

Research Article


Equine conjunctival haemangiosarcoma: Clinical presentation, management, and outcome of seven cases in the United Kingdom

Andrea Kashani-Carver, Conor O'halloran, Emma Scurrell, Heidi Featherstone, Felipe Ferreira de-Freitas, Robert Lowe.


Abstract
Background:
Only 27 cases of equine conjunctival haemangiosarcoma have been reported in the literature over the past 37 years. Out of these, 22% of cases were lost to follow-up, 52% were euthanised and 26% survived. A scarcity of cases and information is available for this rarely seen conjunctival tumour.
Aim:
To describe the clinical features, management, and outcome for conjunctival hemangiosarcoma in seven horses in the UK.
Methods:
Optivet medical records were reviewed for equine cases seen, or advised on, with a histopathological diagnosis of conjunctival haemangiosarcoma between January 2013 and March 2023. Medical records were accessed for details of signalment, history, management, and follow-up. Histopathology was used to confirm the diagnosis of haemangiosarcoma and assess the surgical margins. Immunohistochemistry was performed in a minority of cases with poorly differentiated solid tumours to support vascular lineage.
Results:
Seven eyes from 7 horses (5 geldings and 2 mares) with a mean age of 16 years and median of 18 years (range 10-21 years) met the criteria. Serosanguinous discharge was seen in 6 eyes. All eyes were managed surgically; 4 by exenteration and 3 by conjunctivectomy/keratectomy. Adjunctive cryotherapy was performed in 2 eyes. Metastatic disease in the ipsilateral parotid salivary gland, confirmed with histopathology, was seen in 1 horse. Surgical margins were clear in all but 1 eye. Solar elastosis was noted in 5 eyes. All horses were healthy at the last follow-up (0.2 – 5 years, mean 2.9 years, median 2 years).
Conclusion:
Equine conjunctival haemangiosarcoma is rare. Serosanguinous ocular discharge is a common clinical sign. Early surgical excision is highly effective. Solar elastosis is a common histopathological feature, suggesting a role for UV-light in the pathogenesis.

Key words: Haemangiosarcoma, Solar elastosis, Vascular tumour, Ocular tumour, Conjunctival tumour


 
ARTICLE TOOLS
Abstract
PDF Fulltext
HTML Fulltext
How to cite this articleHow to cite this article
Citation Tools
Related Records
 Articles by Andrea Kashani-Carver
Articles by Conor O'halloran
Articles by Emma Scurrell
Articles by Heidi Featherstone
Articles by Felipe Ferreira de-Freitas
Articles by Robert Lowe
on Google
on Google Scholar


How to Cite this Article
Pubmed Style

Kashani-Carver A, Ohalloran C, Scurrell E, Featherstone H, de-Freitas FF, Lowe R. Equine conjunctival haemangiosarcoma: Clinical presentation, management, and outcome of seven cases in the United Kingdom. Open Vet J. 2023; 13(10): 1366-1378. doi:10.5455/OVJ.2023.v13.i10.17


Web Style

Kashani-Carver A, Ohalloran C, Scurrell E, Featherstone H, de-Freitas FF, Lowe R. Equine conjunctival haemangiosarcoma: Clinical presentation, management, and outcome of seven cases in the United Kingdom. https://www.openveterinaryjournal.com/?mno=162055 [Access: February 12, 2024]. doi:10.5455/OVJ.2023.v13.i10.17


AMA (American Medical Association) Style

Kashani-Carver A, Ohalloran C, Scurrell E, Featherstone H, de-Freitas FF, Lowe R. Equine conjunctival haemangiosarcoma: Clinical presentation, management, and outcome of seven cases in the United Kingdom. Open Vet J. 2023; 13(10): 1366-1378. doi:10.5455/OVJ.2023.v13.i10.17



Vancouver/ICMJE Style

Kashani-Carver A, Ohalloran C, Scurrell E, Featherstone H, de-Freitas FF, Lowe R. Equine conjunctival haemangiosarcoma: Clinical presentation, management, and outcome of seven cases in the United Kingdom. Open Vet J. (2023), [cited February 12, 2024]; 13(10): 1366-1378. doi:10.5455/OVJ.2023.v13.i10.17



Harvard Style

Kashani-Carver, A., Ohalloran, . C., Scurrell, . E., Featherstone, . H., de-Freitas, . F. F. & Lowe, . R. (2023) Equine conjunctival haemangiosarcoma: Clinical presentation, management, and outcome of seven cases in the United Kingdom. Open Vet J, 13 (10), 1366-1378. doi:10.5455/OVJ.2023.v13.i10.17



Turabian Style

Kashani-Carver, Andrea, Conor Ohalloran, Emma Scurrell, Heidi Featherstone, Felipe Ferreira de-Freitas, and Robert Lowe. 2023. Equine conjunctival haemangiosarcoma: Clinical presentation, management, and outcome of seven cases in the United Kingdom. Open Veterinary Journal, 13 (10), 1366-1378. doi:10.5455/OVJ.2023.v13.i10.17



Chicago Style

Kashani-Carver, Andrea, Conor Ohalloran, Emma Scurrell, Heidi Featherstone, Felipe Ferreira de-Freitas, and Robert Lowe. "Equine conjunctival haemangiosarcoma: Clinical presentation, management, and outcome of seven cases in the United Kingdom." Open Veterinary Journal 13 (2023), 1366-1378. doi:10.5455/OVJ.2023.v13.i10.17



MLA (The Modern Language Association) Style

Kashani-Carver, Andrea, Conor Ohalloran, Emma Scurrell, Heidi Featherstone, Felipe Ferreira de-Freitas, and Robert Lowe. "Equine conjunctival haemangiosarcoma: Clinical presentation, management, and outcome of seven cases in the United Kingdom." Open Veterinary Journal 13.10 (2023), 1366-1378. Print. doi:10.5455/OVJ.2023.v13.i10.17



APA (American Psychological Association) Style

Kashani-Carver, A., Ohalloran, . C., Scurrell, . E., Featherstone, . H., de-Freitas, . F. F. & Lowe, . R. (2023) Equine conjunctival haemangiosarcoma: Clinical presentation, management, and outcome of seven cases in the United Kingdom. Open Veterinary Journal, 13 (10), 1366-1378. doi:10.5455/OVJ.2023.v13.i10.17