Open Veterinary Journal

Open Veterinary Journal

Peer-Reviewed Journal 
ISSN 2218-6050 (Online), ISSN 2226-4485 (Print) 

"Review Article"

The treatment of articular cartilage injuries with mesenchymal stem cells in different animal species


Ilnur Ganiev(1*), Natalia Alexandrova(1), Alexander Aimaletdinov(1), Catrin Rutland(2), Albina Malanyeva(1), Albert Rizvanov(1) and Elena Zakirova(1)


1- Institute of Fundamental Medicine and Biology of Kazan (Volga region) Federal University, 18 Kremlin Street, Kazan, Republic of Tatarstan, Russia

2- School of Veterinary Medicine and Science, College Road, Sutton Bonington, University of Nottingham, UK

Abstract

One of the major problems observed in veterinary practice is Articular cartilage injuries in animals. In terms of agriculture, it leads to their culling from the herd, even if they are highly productive animals. With companion animals, owners usually have to decide between euthanasia or long-term sometimes life-long treatment of the injury by a veterinarian. The use of Mesenchymal Stem Cells (MSCs) for the treatment of cartilage injury in veterinary medicine is based on the good results observed in preclinical studies, where large animals have been used as experimental models to study the regenerative activity of MSCs. According to the literature, MSCs in veterinary medicine have been used to treat cartilage injury of dogs and horses, whereas sheep and goats are generally models for reproducing the disease in preclinical experimental studies.

Keywords: Mesenchymal stem cells, Cartilage tissue, Animals, Regeneration, Therapy.

Cite this paper:
Ganiev, I., Alexandrova, N., Aimaletdinov, A., Rutland, C., Malanyeva, A., Rizvanov, A. and Zakirova, E. 2021. The treatment of articular cartilage injuries with mesenchymal stem cells in different animal species. Open Vet. J. 11(1), 128-134.