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2024, Vol: 14, Issue: 4
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Review Article


Host immune responses against African swine fever virus: Insights and challenges for vaccine development

Fredmoore Legaspi Orosco.


Cited By:1

Abstract
The African swine fever virus (ASFV) poses a serious threat to global swine populations, underscoring the urgent need for effective preventive strategies. This comprehensive review investigates the intricate interplay between innate, cellular, and humoral immunity against ASFV, with a focus on their relevance to vaccine development. By delving into immunopathogenesis and immunological challenges, this review article aims to provide a holistic perspective on the complexities of ASFV infections and immune evasion. Key findings underscore the critical role of innate immune recognition in shaping subsequent adaptive immune defenses, potential protective antigens, and the multifaceted nature of ASFV-specific antibodies and cytotoxic T cell responses. Despite advancements, the unique attributes of ASFV present hurdles in the development of a successful vaccine. In conclusion, this review examines the current state of ASFV immune responses and offers insights into future research directions, fostering the development of effective interventions against this devastating pathogen.

Key words: African swine fever virus, Immune response, Swine industry, Vaccine development


 
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How to Cite this Article
Pubmed Style

Fredmoore Legaspi Orosco. Host immune responses against African swine fever virus: Insights and challenges for vaccine development. Open Vet J. 2023; 13(12): 1517-1535. doi:10.5455/OVJ.2023.v13.i12.2

Web Style

Fredmoore Legaspi Orosco. Host immune responses against African swine fever virus: Insights and challenges for vaccine development. https://www.openveterinaryjournal.com/?mno=168751 [Access: May 02, 2024]. doi:10.5455/OVJ.2023.v13.i12.2

AMA (American Medical Association) Style

Fredmoore Legaspi Orosco. Host immune responses against African swine fever virus: Insights and challenges for vaccine development. Open Vet J. 2023; 13(12): 1517-1535. doi:10.5455/OVJ.2023.v13.i12.2


Vancouver/ICMJE Style

Fredmoore Legaspi Orosco. Host immune responses against African swine fever virus: Insights and challenges for vaccine development. Open Vet J. (2023), [cited May 02, 2024]; 13(12): 1517-1535. doi:10.5455/OVJ.2023.v13.i12.2


Harvard Style

Fredmoore Legaspi Orosco (2023) Host immune responses against African swine fever virus: Insights and challenges for vaccine development. Open Vet J, 13 (12), 1517-1535. doi:10.5455/OVJ.2023.v13.i12.2


Turabian Style

Fredmoore Legaspi Orosco. 2023. Host immune responses against African swine fever virus: Insights and challenges for vaccine development. Open Veterinary Journal, 13 (12), 1517-1535. doi:10.5455/OVJ.2023.v13.i12.2


Chicago Style

Fredmoore Legaspi Orosco. "Host immune responses against African swine fever virus: Insights and challenges for vaccine development." Open Veterinary Journal 13 (2023), 1517-1535. doi:10.5455/OVJ.2023.v13.i12.2


MLA (The Modern Language Association) Style

Fredmoore Legaspi Orosco. "Host immune responses against African swine fever virus: Insights and challenges for vaccine development." Open Veterinary Journal 13.12 (2023), 1517-1535. Print. doi:10.5455/OVJ.2023.v13.i12.2


APA (American Psychological Association) Style

Fredmoore Legaspi Orosco (2023) Host immune responses against African swine fever virus: Insights and challenges for vaccine development. Open Veterinary Journal, 13 (12), 1517-1535. doi:10.5455/OVJ.2023.v13.i12.2


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