Open Veterinary Journal

Peer-Reviewed Journal 
ISSN 2218-6050 (Online), ISSN 2226-4485 (Print) 

"Short Communication"

Dual natural infection with bovine viral diarrhea virus -1 and -2 in a stillborn calf: tissue distribution and molecular characterization


Maximiliano J. Spetter(1,2,‡), Enrique L. Louge Uriarte(2,‡), Erika A. González Altamiranda(2,3), María R. Leunda(2), Susana B. Pereyra(2), Andrea E. Verna(2,3) and 

Anselmo C. Odeón(2,*)


Fondo para la Investigación Científica y Tecnológica (FONCYT), Godoy Cruz 2370 2° piso, Buenos Aires (C1425FQD), Argentina

Grupo de Sanidad Animal, Área de Producción Animal, INTA EEA Balcarce, Ruta 226, km 73.5 (CP 7620), Argentina

Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Avenida Rivadavia 1917, Buenos Aires (C1033AAJ), Argentina

‡ Contributed equally to this work

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Abstract

Dual infections with both bovine viral diarrhea virus (BVDV)-1 and -2 seem to be unusual. The aim of this study was to describe an infection with both BVDV genotypes in a stillborn calf. Virus isolation and phylogenetic analyses of the 5´UTR and NS5B regions confirmed the presence of BVDV-1b and -2b in spleen and lung, whereas BVDV-2b was also detected in brain, heart, liver, kidney and, fluid of cavities. These results confirm that dual infections with both BVDV-1 and BVDV-2 species can occur naturally and their tissue distribution can be different.

Keywords: Bovine viral diarrhea virus, Co-infection, Phylogenetic analysis.

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Cite this paper:

Spetter, M.J., Louge Uriarte, E.L., González Altamiranda, E.A., Leunda, M.R., Pereyra, S.B., Verna, A.E. and Odeón, A.C. 2018. Dual natural infection with bovine viral diarrhea virus -1 and -2 in a stillborn calf: tissue distribution and molecular characterization. Open Vet. J. 8(4), 493-497.