Felipe Lara(1), Rodrigo Castro(2) and Pamela Thomson(3*)
1- Unidad de Medicina y Cirugía Equina, Hospital Clínico Veterinario, Escuela de Medicina Veterinaria, Facultad de Ciencias de la Vida, Universidad Andrés Bello, Santiago, Chile
2- Escuela de Medicina Veterinaria, Facultad de Recursos Naturales y Medicina Veterinaria, Universidad Santo Tomás, Chile
3- Laboratorio Microbiología Clínica y Microbioma, Escuela de Medicina Veterinaria, Facultad de Ciencias de la Vida, Universidad Andrés Bello, Santiago, Chile
The gut microbiome is compound for millions of microorganisms that coexist in an organized way and contribute to the fermentation of different types of indigestible fibers by the small intestine. Some techniques such as the massive sequencing of the 16S ribosomal RNA gene have made it possible to obtain information about the abundance and functionality of the microorganisms that compose the equine gut microbiome and the interaction with their environment. Recent studies have identified the change in the composition of the intestinal microbiome during and after a colic episode, although is not clear that is cause or consequence. The objective of this review was to elucidate whether there is a direct relationship between the changes that occur in the gut microbiome and colic in the equine. A systematized search in Embase, Web of Science and Pubmed was realized. Although there is good evidence that horses with colic have a change in their gut microbiome, it is not fully understood whether these changes are cause or effect. It is necessary to delve into this topic, considering studying larger population sizes, in addition, it would be of great value to previously know the normal intestinal microbiome of a group of healthy horses, which in the future could develop an episode of colic, to compare the before and after in the same individual.
Keywords: Colic, Equine, Gut, Microbiome.