Open Veterinary Journal

Peer-Reviewed Journal

A rare case of pituitary chromophobe carcinoma in a dog: clinical, tomographic and histopathological findings


M. Longo(1,2,*), D. Binanti(3), P.G. Zagarella(2), F. Iocca(2), D. De Zani(1), G. Ravasio(1), M. Di Giancamillo(1) and

D.D. Zani(1)


1 Dipartimento di Medicina Veterinaria (DIMEVET), Università degli Studi di Milano, Az.Polo Veterinario di Lodi, Lodi, Italy

2 Centro Traumatologico Ortopedico Veterinario, Arenzano (GE), Italy

3 AbLab, Veterinary Diagnostic Laboratory, Sarzana (SP), Italy
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Abstract

A 9 year old male mixed-breed dog was presented for progressive aggressiveness towards the owner. The neurological evaluation was consistent with a forebrain syndrome. Magnetic Resonance Imaging (MRI) of the brain revealed enlargement of the third ventricle and presence of a large spheroidal neoplasm in the sellar/parasellar region suggestive of a pituitary macroadenoma. On the owner request, the dog was euthanized. Histopathological examination revealed the presence of a pituitary chromophobe carcinoma. To the author’s knowledge, pituitary carcinomas have been rarely described in dogs, especially the chromophobe subtype.

Keywords: Brain, Chromophobe carcinoma, Histology, Pituitary neoplasm, Tumour.

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Cite this paper:
Longo, M., Binanti, D., Zagarella, P.G., Iocca, F., De Zani, D., Ravasio, G., Di Giancamillo, M. and Zani, D.D. 2016. A rare case of pituitary chromophobe carcinoma in a dog: clinical, tomographic and histopathological findings. Open Vet. J. 6(3), 158-161.