Open Veterinary Journal

Peer-Reviewed Journal

 

Intravenous lipid emulsion and dexmedetomidine for treatment of feline permethrin intoxication: a report from 4 cases

G. Ceccherini1,*, F. Perondi1, I. Lippi1,2, G. Guidi1 and V. Marchetti1

1Department of Veterinary Science, Veterinary Teaching Hospital ‘Mario Modenato’, University of Pisa, via Livornese Lato Monte, 56122 S. Piero a Grado (Pisa), Italy

2UC Veterinary Medical Center San Diego 10435 Sorrento Valley Rd, Suite 101, San Diego, CA 92121, USA

___________________________________________________________________________

Abstract

Four cases of feline permethrin intoxication are described. The cause of intoxication is the application of canine permethrin spot-on product (Advantix®, Bayer) by the owners. Principal clinical guidelines recommends the use of anticonvulsant drugs to treat seizures or neurological symptoms after initial stabilization and dermal decontamination. The use of lipid emulsion had an increasing interest in the last decade for treatment of toxicosis caused by lipophilic drugs as reported in human and in veterinary medical practices. All cats presented in this study, were treated with intravenous lipid emulsion (ILE) at variable dosages, and dexmedetomidine was also administered by intravenous way. No adverse reaction such as thrombophlebitis, overload circulation or others was noticed during and after administration of ILE. Dexmedetomidine was proved to be helpful in tranquillizing the cats. All cats were discharged in good condition faster than other cases treated without their use.

Keywords: Cat, Dexmedetomidine, Intravenous lipid emulsion, Permethrin.

___________________________________________________________________________

Cite this paper:

Ceccherini, G., Perondi, F., Lippi, I., Grazia, G. and Marchetti, V. 2015. Intravenous lipid emulsion and dexmedetomidine for treatment of feline permethrin intoxication: a report from 4 cases. Open Vet. J. 5(2), 113-121.