Open Veterinary Journal

Peer-Reviewed Journal

"Original Article"

Analysis of serum magnesium ions in dogs exposed to external stress: A pilot study


Izumi Ando(1), Kaoru Karasawa(1,2), Shinichi Yokota(3), Takao Shioya(4), Hiroshi Matsuda(1,3) and Akane Tanaka(1,2,*)


Cooperative Major in Advanced Health Science, Graduate School of Bio-Applications and System Engineering, Tokyo University of Agriculture and Technology, Tokyo 183-8509, Japan

Laboratory of Comparative Animal Medicine, Division of Animal Life Science, Institute of Agriculture, Tokyo University of Agriculture and Technology, Tokyo 183-8509, Japan

Laboratory of Veterinary Molecular Pathology and Therapeutics, Division of Animal Life Science, Institute of Agriculture, Tokyo University of Agriculture and Technology, Tokyo 183-8509, Japan

The Eye Mate Inc., Tokyo 177-0051, Japan

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Abstract

Magnesium ions (Mg2+) are essential for various enzymatic reactions in the body associated with energy production and activation of the muscles and nerves. Mg2+ is also involved in blood pressure regulation, maintenance of body temperature, and glucose metabolism. Although various factors including foods and physical conditions have been reported to change serum Mg2+ status in humans, serum Mg2+ in dogs exposed to external stress has been unclear. In this study, we examined serum levels of Mg2+ in dogs at different conditions using the guide dog candidates for the blind. Serum Mg2+ was decreased in winter and increased in summer. Guide dog candidates in an elementary class of the training showed markedly lower levels of serum Mg2+, compared with that of dogs in an advanced class. When healthy adult dogs were subjected to forced exercise using a treadmill, a significant reduction in serum Mg2+ levels was observed, particularly in winter. These findings suggest that serum levels of Mg2+ may be influenced by weather fluctuation such as air temperature, nervousness in unaccustomed situations, age, and physical stress induced by exercise. The results indicate that Mg2+ supplementation should be considered for working dogs, dogs moving or traveling to a new environment, and dogs during winter.

Keywords: Exercise, Guide dogs, Seasonality, Serum magnesium ions, Training.

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Cite this paper:

Ando, I., Karasawa, K., Yokota, S., Shioya, T., Matsuda, H. and Tanaka, A. 2017. Analysis of serum magnesium ions in dogs exposed to external stress: A pilot study. Open Vet. J. 7(4), 367-374.